Ralph Holsworth, DO

Board-certified physician in Family Medicine, researcher and former commissioned officer in the United States Public Health Service.


Dr. Ralph E. Holsworth, Jr., D.O. is a board-certified physician in Family Medicine who is internationally known through his research and publications in the area of enzyme enhanced medical treatment.

Dr. Holsworth is a former commissioned officer in the United States Public Health Service. He is also an international guest speaker at medical conferences and conventions.

He earned his Bachelor of Science degree in Geochemistry at the University of Texas in 1985 and his Doctorate of Osteopathy in 1997 from the College of Osteopathic Medicine in Kansas City, Missouri. He has been practicing as a family medicine physician with an emphasis on functional and integrative medicine since graduation.

His specific interests are in systemic enzyme therapy where he has been involved in clinical and laboratory research for over a decade. His medical licensing is through the State of Colorado.

His background includes service as a medical staff officer for the U.S. Public Health Services. He also was an Honorary Professor in the Department of Biology at the University of Colorado in 2001. Further professional experiences include participation in the review of clinical trials of Wormwood Treatment for Cancer in 1998 at the National Academy of Science in Kazakhstan. In 1997, Dr. Holsworth worked as a research assistant in the area of Oral Systemic Enzymes as Adjuvant Cancer Treatment at The Cancer Treatment Center of Tulsa in Oklahoma.

His recent research with the USC’s Keck School of Medicine demonstrated nattokinase’s therapeutic ability to lower human blood viscosity (a “true blood-thinner”) and to prevent the aggregation of red blood cells and platelets. Currents studies involve nattokinase’s enhancement of fibrinolysis and drug delivery mechanisms to potentiate nattokinase’s pharmokinectics.